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Review
. 2014 Aug;55(3):169-75.
doi: 10.1111/ajd.12163. Epub 2014 Mar 17.

Nicotinamide and the skin

Andrew C Chen  1 , Diona L Damian
Affiliations
Review

Nicotinamide and the skin

Andrew C Chen et al. Australas J Dermatol. 2014 Aug.

Abstract

Nicotinamide, an amide form of vitamin B3, boosts cellular energy and regulates poly-ADP-ribose-polymerase 1, an enzyme with important roles in DNA repair and the expression of inflammatory cytokines. Nicotinamide shows promise for the treatment of a wide range of dermatological conditions, including autoimmune blistering disorders, acne, rosacea, ageing skin and atopic dermatitis. In particular, recent studies have also shown it to be a potential agent for reducing actinic keratoses and preventing skin cancers.

Keywords: nicotinamide; skin cancer; skin disease.

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