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Review
. 2014 Apr;35(4):139-40.
doi: 10.1016/j.it.2014.02.005. Epub 2014 Mar 11.

Microglia fuel the learning brain

Thomas Blank  1 , Tobias Goldmann  1 , Marco Prinz  2
Affiliations
Review

Microglia fuel the learning brain

Thomas Blank et al. Trends Immunol. 2014 Apr.

Abstract

Microglia, the brain resident macrophages, are first responders to any violation of central nervous system (CNS) homeostasis. A recent paper in Cell shows that the specific depletion of microglia causes deficits in learning-induced synaptic remodeling through paucity of the microglial neurotrophin brain-derived neurotrophic factor (BDNF).

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