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. 2014 Mar;17(2):261-5.
doi: 10.1016/j.jval.2013.12.002.

Should linking replace regression when mapping from profile-based measures to preference-based measures?

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Should linking replace regression when mapping from profile-based measures to preference-based measures?

Peter M Fayers et al. Value Health. 2014 Mar.

Abstract

Background: Profile instruments are frequently used to assess health-related quality of life and other patient-reported outcomes. However, preference-based measures are required for health-economic cost-utility evaluations.

Results: Although regression-based approaches are commonly used to map from profile measures to preference measures, we show that this results in biased estimates because of regression to the mean.

Conclusions: Linking (scale-aligning) is proposed as an alternative.

Keywords: linking values; mapping functions; patient-reported outcomes; preference-based measures; profile instruments; scale-aligning; test equating.

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References

    1. Fayers PM, Machin D. Quality of Life: The assessment, analysis and interpretation of patient-reported outcomes. 2. Chichester: Wiley & Sons Ltd; 2007.
    1. Hunt SM, McEwan J. The development of a subjective health indicator. Sociol Health Illness. 1980;2:231–46. - PubMed
    1. Hays RD, Mangione CM, Ellwein L, et al. Psychometric properties of the National Eye Institute – Refractive Error Quality of Life Instrument. Ophthalmology. 2003;110:2292–01. - PubMed
    1. Revicki DA, Kawata AK, Harnam N, et al. Predicting EuroQol (EQ-5D) scores from the Patient-Reported Outcomes Measurement Information System (PROMIS) Global items and domain item banks in a United States sample. Qual Life Res. 2009;18:783–91. - PMC - PubMed
    1. Kowalski JW, Rentz AM, Walt JG, et al. Rasch analysis in the development of a simplified version of the National Eye Institute Visual-Function Questionnaire-25 for utility estimation. Qual Life Res. 2011;21:323–34. - PubMed

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