Should linking replace regression when mapping from profile-based measures to preference-based measures?
- PMID: 24636385
- PMCID: PMC4232819
- DOI: 10.1016/j.jval.2013.12.002
Should linking replace regression when mapping from profile-based measures to preference-based measures?
Abstract
Background: Profile instruments are frequently used to assess health-related quality of life and other patient-reported outcomes. However, preference-based measures are required for health-economic cost-utility evaluations.
Results: Although regression-based approaches are commonly used to map from profile measures to preference measures, we show that this results in biased estimates because of regression to the mean.
Conclusions: Linking (scale-aligning) is proposed as an alternative.
Keywords: linking values; mapping functions; patient-reported outcomes; preference-based measures; profile instruments; scale-aligning; test equating.
Copyright © 2014 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.
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