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Editorial
. 2014 Apr;16(4):471-2.
doi: 10.1093/neuonc/nou037.

Chemoprevention for neurofibromatosis 2: just over the horizon?

Scott R Plotkin  1
Affiliations
Editorial

Chemoprevention for neurofibromatosis 2: just over the horizon?

Scott R Plotkin. Neuro Oncol. 2014 Apr.
No abstract available

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Comment on

  • mTORC1 inhibition delays growth of neurofibromatosis type 2 schwannoma.
    Giovannini M, Bonne NX, Vitte J, Chareyre F, Tanaka K, Adams R, Fisher LM, Valeyrie-Allanore L, Wolkenstein P, Goutagny S, Kalamarides M. Giovannini M, et al. Neuro Oncol. 2014 Apr;16(4):493-504. doi: 10.1093/neuonc/not242. Epub 2014 Jan 10. Neuro Oncol. 2014. PMID: 24414536 Free PMC article.

References

    1. Evans DG, Moran A, King A, Saeed S, Gurusinghe N, Ramsden R. Incidence of vestibular schwannoma and neurofibromatosis 2 in the North West of England over a 10-year period: higher incidence than previously thought. Otol Neurotol. 2005;26:93–97. - PubMed
    1. Plotkin SR, Merker VL, Muzikansky A, Barker FG, Slattery W., III Natural history of vestibular schwannoma growth and hearing decline in newly diagnosed neurofibromatosis type 2 patients. Otol Neurotol. 2014;35:e50–e56. - PubMed
    1. Smith MJ, Higgs JE, Bowers NL, et al. Cranial meningiomas in 411 neurofibromatosis type 2 (NF2) patients with proven gene mutations: clear positional effect of mutations, but absence of female severity effect on age at onset. J Med Genet. 2011;48:261–265. - PubMed
    1. Doherty JK, Ongkeko W, Crawley B, Andalibi A, Ryan AF. ErbB and Nrg: potential molecular targets for vestibular schwannoma pharmacotherapy. Otol Neurotol. 2008;29:50–57. - PubMed
    1. Curto M, Cole BK, Lallemand D, Liu CH, McClatchey AI. Contact-dependent inhibition of EGFR signaling by Nf2/Merlin. J Cell Biol. 2007;177:893–903. - PMC - PubMed

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