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. 2014;228(3):261-8.
doi: 10.1159/000358009. Epub 2014 Mar 7.

Self-reported skin morbidities and health-related quality of life: a population-based nested case-control study

G R Vinding  1 , K M Knudsen, C Ellervik, A B Olesen, G B E Jemec
Affiliations

Self-reported skin morbidities and health-related quality of life: a population-based nested case-control study

G R Vinding et al. Dermatology. 2014.

Abstract

Background: Impaired dermatological health-related quality of life (HRQoL) has been observed in hospital-based studies, but little is known on a population-based level.

Objective: To investigate self-reported dermatological HRQoL in the general population.

Methods: Hidradenitis suppurativa, psoriasis, pimples, hand rash or atopic eczema were identified using questionnaires in a 15,177 person population sample. A nested case-control study of 180 cases and 259 controls was made using the Dermatology Life Quality Index (DLQI), Skindex-29 and EQ-5D.

Results: Cases had higher scores in DLQI and Skindex-29 and a lower score in EQ-5D, suggesting lower HRQoL. Adjusting for age and sex, the differences in Skindex-29 and DLQI were significant (p < 0.001).

Conclusions: Persons with self-reported skin morbidity had lower HRQoL than the general population. The impairment is not as significant as in studies of hospital-based cases, but considering the high prevalence of skin diseases it may still represent a significant burden of disease on society in aggregate.

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