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. 2014 Feb;26(1):129-32.
doi: 10.5021/ad.2014.26.1.129. Epub 2014 Feb 17.

Biological effects of femtosecond-terahertz pulses on C57BL/6 mouse skin

Seong Jin Jo  1 , Sun-Young Yoon  1 , Ji Yeon Lee  1 , Kyu-Tae Kim  2 , Seonghoon Jung  3 , Jaehun Park  3 , Gun-Sik Park  4 , Woong-Yang Park  2 , Ohsang Kwon  5
Affiliations

Biological effects of femtosecond-terahertz pulses on C57BL/6 mouse skin

Seong Jin Jo et al. Ann Dermatol. 2014 Feb.
No abstract available

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Figures

Fig. 1
Fig. 1
Histological observations on the back skin of C57BL/6 mice exposed to the femtosecond-Terahertz (fs-THz) beam for 1 hour (H&E; ×200 and ×400). Skin samples were biopsied at 1 and 24 hours after exposure.
Fig. 2
Fig. 2
Gene expression in the femtosecond-Terahertz (fs-THz)-irradiated mouse skin. The back skin of C57BL/6 mice (sham, n=4; fs-THz, n=5; A~D) and BALB/c nude mice (sham, n=3; fs-THz, n=4; E~F) were exposed to the fs-THz beam for 1 hour. Skin samples were biopsied either at 1 and 24 hours after exposure of C57BL/6 mice or at 12 and 36 hours after exposure of BALB/C nude mice. Real-time quantitative polymerase chain reaction was used for gene expression survey: (A) substance P, (B) calcitonin gene-related peptide, (C, E) transient receptor potential vanilloid1 (TRPV1), (D, F) TRPV4. Results were expressed as mean±standard error of the mean. *p<0.05, compared to the nonirradiated sham group.
See this image and copyright information in PMC

References

    1. Smye SW, Chamberlain JM, Fitzgerald AJ, Berry E. The interaction between Terahertz radiation and biological tissue. Phys Med Biol. 2001;46:R101–R112. - PubMed
    1. Joseph CS, Yaroslavsky AN, Neel VA, Goyette TM, Giles RH. Continuous wave terahertz transmission imaging of nonmelanoma skin cancers. Lasers Surg Med. 2011;43:457–462. - PubMed
    1. Möller L, Federici J, Sinyukov A, Xie C, Lim HC, Giles RC. Data encoding on terahertz signals for communication and sensing. Opt Lett. 2008;33:393–395. - PubMed
    1. Grossman E, Dietlein C, Ala-Laurinaho J, Leivo M, Gronberg L, Gronholm M, et al. Passive terahertz camera for standoff security screening. Appl Opt. 2010;49:E106–E120. - PubMed
    1. Szabo I, Manning MR, Radzievsky AA, Wetzel MA, Rogers TJ, Ziskin MC. Low power millimeter wave irradiation exerts no harmful effect on human keratinocytes in vitro. Bioelectromagnetics. 2003;24:165–173. - PubMed

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