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Review
. 2014 Mar 10:8:83-90.
doi: 10.2147/BTT.S46469. eCollection 2014.

Porcine dermis implants in soft-tissue reconstruction: current status

Neil J Smart  1 , Nicholas Bryan  2 , John A Hunt  2 , Ian R Daniels  1
Affiliations
Review

Porcine dermis implants in soft-tissue reconstruction: current status

Neil J Smart et al. Biologics. .

Abstract

Soft-tissue reconstruction for a variety of surgical conditions, such as abdominal wall hernia or pelvic organ prolapse, remains a challenge. There are numerous meshes available that may be simply categorized as either synthetic or biologic. Within biologic meshes, porcine dermal meshes have come to dominate the market. This review examines the current evidence for their use and the limitations of knowledge. Although there is increasing evidence to support their safety, long-term follow-up studies that support their efficacy are lacking. Numerous clinical trials that remain ongoing may help elucidate their precise role in soft-tissue reconstruction.

Keywords: biologic; hernia; mesh; xenograft.

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Figures

Figure 1
Figure 1
Retrorectus placement of porcine dermal mesh (Permacol™; Covidien, New Haven, CT, USA) in abdominal wall reconstruction for recurrent incisional hernia repair. Notes: The anterior rectus sheath is being approximated with interrupted polypropylene sutures.
Figure 2
Figure 2
Underlay placement of porcine dermal mesh (Strattice™; LifeCell Corporation, Bridgewater, NJ, USA) in abdominal wall reconstruction for incisional hernia repair in a patient with a previous stoma. Reproduced from Guerra O, Maclin MM. Non-crosslinked porcine-derived acellular dermal matrix for the management of complex ventral abdominal wall hernias: a report of 45 cases. Hernia. Epub 2013 Aug 10.
Figure 3
Figure 3
Perineal reconstruction with porcine dermal mesh (Permacol™; Covidien, New Haven, CT, USA) following extralevator abdominoperineal excision for low rectal cancer. Notes: The porcine dermal mesh has been sutured to the divided edges of the levators laterally and to the presacral fascia posteriorly. Anteriorly, the mesh is folded to form a “U” shape that abuts the posterior wall of the vagina in females and the prostate in males.
See this image and copyright information in PMC

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