Bloodless surgery in a pediatric Jehovah's Witness
- PMID: 24649574
- PMCID: PMC4557499
Bloodless surgery in a pediatric Jehovah's Witness
Abstract
Pediatric cardiac surgery in Jehovah's Witness patients who refuse the use of blood products remains a challenge because of the extreme hemodilution caused by priming the circuit and subsequent cardiopulmonary bypass. We report our successful strategy for reducing the prime volume for a 2-year-old Jehovah's Witness patient who required open heart surgery. We modified our conventional bypass circuit requirements for this size child by incorporating a lower prime oxygenator and reducing the size of the venous line and circuit, which decreased the circuit prime volume. We managed to reduce our initial sanguineous prime volume from 315 to 210 mL. The prime was further reduced to 160 mL by minimizing circuit length at the field and with venous prime sequestration prebypass. The postbypass hematocrit was 31%. Bloodless pediatric cardiac surgery in Jehovah's Witness patients can be performed safely. Incorporating a lower prime oxygenator into a revised circuit alleviated the need for blood transfusion and allowed us to achieve our calculated flow rate of 2.6 L/min/m2 while maintaining a hematocrit of 31%.
Conflict of interest statement
The senior author has stated that the authors have reported no material, financial, or other relationship with any healthcare-related business or other entity whose products or services are discussed in this paper.
Similar articles
-
Bloodless Heart Surgery for an 11-kg Infant of the Jehovah's Witness Faith Undergoing Second Repair for Complete Atrioventricular Canal.J Extra Corpor Technol. 2018 Sep;50(3):184-186. J Extra Corpor Technol. 2018. PMID: 30250346 Free PMC article.
-
Bloodless Repair of Aortic Arch with Dual Aortic Cannulation in a Jehovah's Witness Patient.J Extra Corpor Technol. 2017 Sep;49(3):206-209. J Extra Corpor Technol. 2017. PMID: 28979046 Free PMC article.
-
Bloodless Repair for a 3.6 Kilogram Transposition of the Great Arteries with Jehovah's Witness Faith.J Extra Corpor Technol. 2017 Dec;49(4):307-311. J Extra Corpor Technol. 2017. PMID: 29302123 Free PMC article.
-
Jehovah's Witnesses: Challenges in liver disease management and in liver transplantation.Liver Transpl. 2025 May 1;31(5):682-693. doi: 10.1097/LVT.0000000000000514. Epub 2024 Oct 16. Liver Transpl. 2025. PMID: 39569989 Review.
-
Strategic and operational aspects of a transfusion-free neonatal arterial switch operation.Interact Cardiovasc Thorac Surg. 2013 Jun;16(6):890-1. doi: 10.1093/icvts/ivt010. Epub 2013 Mar 4. Interact Cardiovasc Thorac Surg. 2013. PMID: 23460601 Free PMC article. Review.
Cited by
-
Superior blood-saving effect and postoperative recovery of comprehensive blood-saving strategy in infants undergoing open heart surgery under cardiopulmonary bypass.Medicine (Baltimore). 2018 Jul;97(27):e11248. doi: 10.1097/MD.0000000000011248. Medicine (Baltimore). 2018. PMID: 29979388 Free PMC article. Clinical Trial.
-
Functional Performance of Different Venous Limb Options in Simulated Neonatal/Pediatric Cardiopulmonary Bypass Circuits.Braz J Cardiovasc Surg. 2018 May-Jun;33(3):224-232. doi: 10.21470/1678-9741-2018-0074. Braz J Cardiovasc Surg. 2018. PMID: 30043914 Free PMC article.
-
Pediatric Perioperative Clinical Pharmacy Practice: Clinical Considerations and Management: An Opinion of the Pediatrics and Perioperative Care Practice and Research Networks of the American College of Clinical Pharmacy.J Pediatr Pharmacol Ther. 2022;27(6):490-505. doi: 10.5863/1551-6776-27.6.490. Epub 2022 Aug 19. J Pediatr Pharmacol Ther. 2022. PMID: 36042955 Free PMC article.
-
Refusal of Medical Blood Transfusions Among Jehovah's Witnesses: Emotion Regulation of the Dissonance of Saving and Sacrificing Life.J Relig Health. 2016 Oct;55(5):1672-87. doi: 10.1007/s10943-016-0236-5. J Relig Health. 2016. PMID: 27094707
References
-
- Miyaji KA, Kohira SA, Miyamoto TA, et al. . Pediatric cardiac surgery without homologous blood transfusion, using a miniaturized bypass system in infants with lower body weight. J Thorac Surg. 2007;134:284–289. - PubMed
-
- Forest RJ, Groom RC, Quinn R, Donnelly J, Clark C.. Repair of hypoplastic left heart syndrome in a 4.25 kg Jehovah’s Witness. Perfusion. 2002;17:221–225. - PubMed
-
- Karimi MO, Florentino-Pineda IV, Weatherred TE, et al. . Blood conservation operations in pediatric cardiac patients: A paradigm shift of blood use. Ann Thorac Surg. 2013;95:962–967. - PubMed
-
- Nakanishi K, Shichijo T, Shinkawa Y, et al. . Usefulness of vacuum-assisted cardiopulmonary bypass circuit for pediatric open-heart surgery in reducing homologous blood transfusion. Eur J Cardiothorac Surg. 2001;20:233–238. - PubMed
-
- Utley JR, Stephens DB, Wachtel C, et al. . Effect of albumin and mannitol on organ blood flow, oxygen delivery, water content and renal function during hypothermic hemodilution cardiopulmonary bypass. Ann Thorac Surg. 1982;33:250–257. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources