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. 2014 Mar 20;9(3):e92150.
doi: 10.1371/journal.pone.0092150. eCollection 2014.

Electrolyte disorders and in-hospital mortality during prolonged heat periods: a cross-sectional analysis

Carmen A Pfortmueller  1 , Georg-Christian Funk  2 , Alexander B Leichtle  3 , Georg M Fiedler  3 , Christoph Schwarz  4 , Aristomenis K Exadaktylos  5 , Gregor Lindner  5
Affiliations

Electrolyte disorders and in-hospital mortality during prolonged heat periods: a cross-sectional analysis

Carmen A Pfortmueller et al. PLoS One. .

Abstract

Background: Heat periods during recent years were associated with excess hospitalization and mortality rates, especially in the elderly. We intended to study whether prolonged warmth/heat periods are associated with an increased prevalence of disorders of serum sodium and potassium and an increased hospital mortality.

Methods: In this cross-sectional analysis all patients admitted to the Department of Emergency Medicine of a large tertiary care facility between January 2009 and December 2010 with measurements of serum sodium were included. Demographic data along with detailed data on diuretic medication, length of hospital stay and hospital mortality were obtained for all patients. Data on daily temperatures (maximum, mean, minimum) and humidity were retrieved by Meteo Swiss.

Results: A total of 22.239 patients were included in the study. 5 periods with a temperature exceeding 25 °C for 3 to 5 days were noticed and 2 periods with temperatures exceeding 25 °C for more than 5 days were noted. Additionally, 2 periods with 3 to 5 days with daily temperatures exceeding 30 °C were noted during the study period. We found a significantly increased prevalence of hyponatremia during heat periods. However, in the Cox regression analysis, prolonged heat was not associated with the prevalence of disorders of serum sodium or potassium. Admission during a heat period was an independent predictor for hospital mortality.

Conclusions: Although we found an increased prevalence of hyponatremia during heat periods, no convincing connection could be found for hypernatremia or disorders of serum potassium.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Monthly prevalence of electrolyte disorders.
Numbers are given in percent.
See this image and copyright information in PMC

References

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