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Randomized Controlled Trial
. 2014 Apr;102(4):374-82.
doi: 10.5935/abc.20140029. Epub 2014 Feb 17.

Alimentary habits, physical activity, and Framingham global risk score in metabolic syndrome

[Article in English, Portuguese]
Thays Soliman Soares, Carla Haas Piovesan, Andréia da Silva Gustavo, Fabrício Edler Macagnan, Luiz Carlos Bodanese, Ana Maria Pandolfo Feoli
Randomized Controlled Trial

Alimentary habits, physical activity, and Framingham global risk score in metabolic syndrome

[Article in English, Portuguese]
Thays Soliman Soares et al. Arq Bras Cardiol. 2014 Apr.

Abstract

Background: Metabolic syndrome is a complex disorder represented by a set of cardiovascular risk factors. A healthy lifestyle is strongly related to improve Quality of Life and interfere positively in the control of risk factors presented in this condition.

Objective: To evaluate the effect of a program of lifestyle modification on the Framingham General Cardiovascular Risk Profile in subjects diagnosed with metabolic syndrome.

Methods: A sub-analysis study of a randomized clinical trial controlled blind that lasted three months. Participants were randomized into four groups: dietary intervention + placebo (DIP), dietary intervention + supplementation of omega 3 (fish oil 3 g/day) (DIS3), dietary intervention + placebo + physical activity (DIPE) and dietary intervention + physical activity + supplementation of omega 3 (DIS3PE). The general cardiovascular risk profile of each individual was calculated before and after the intervention.

Results: The study included 70 subjects. Evaluating the score between the pre and post intervention yielded a significant value (p < 0.001). We obtained a reduction for intermediate risk in 25.7% of subjects. After intervention, there was a significant reduction (p < 0.01) on cardiovascular age, this being more significant in groups DIP (5.2%) and DIPE (5.3%).

Conclusion: Proposed interventions produced beneficial effects for reducing cardiovascular risk score. This study emphasizes the importance of lifestyle modification in the prevention and treatment of cardiovascular diseases.

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Conflict of interest statement

Potential Conflict of Interest

No potential conflict of interest relevant to this article was reported.

Figures

Figure 1
Figure 1
Study scheme. DIP: dietary intervention; DIPE: dietary intervention + physical activity; DIS3: dietary intervention + omega 3 fatty acid supplementation; DIS3PE: dietary intervention + physical activity + omega 3 fatty acid supplementation.
See this image and copyright information in PMC

References

    1. Brandão AP, Brandão AA, Nogueira AR, Suplicy H, Guimarães JI, Oliveira JE, et al. Sociedade Brasileira de Cardiologia I Diretriz brasileira de diagnóstico e tratamento da síndrome metabólica. Arq Bras Cardiol. 2005;84(supl 1):1–28. - PubMed
    1. World Health Organization. (WHO) Noncommunicable diseases country profiles, 2011. [Cited 2012 Nov 13]. Available from: http://www.who.int/nmh/countries/bra_en.pdf.
    1. D'Andrea F, Giugliano D. Effect of a mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: a randomized trial. JAMA. 2004;292(12):1440–1446. - PubMed
    1. Villareal DT, Miller BV, Banks M, Fontana L, Sinacore DR, Klein S. Effect of lifestyle intervention on metabolic coronary heart disease risk factors in obese older adults. Am J Clin Nutr. 2006;84(6):1317–1323. - PubMed
    1. Calder PC, Ahluwalia N, Brouns F, Buetler T, Clement K, Cunningham K, et al. Dietary factors and low-grade inflammation in relation to overweight and obesity. Br J Nutr. 2011;106(Suppl 3):S5–78. - PubMed

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