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. 2014 Aug;3(8):1194-9.
doi: 10.1002/adhm.201300597. Epub 2014 Mar 20.

Gold nanoparticles displaying tumor-associated self-antigens as a potential vaccine for cancer immunotherapy

Sukyung Ahn  1 , In-Hyun Lee, Sukmo Kang, Daejin Kim, Minsuk Choi, Phei Er Saw, Eui-Cheol Shin, Sangyong Jon
Affiliations

Gold nanoparticles displaying tumor-associated self-antigens as a potential vaccine for cancer immunotherapy

Sukyung Ahn et al. Adv Healthc Mater. 2014 Aug.

Abstract

Golden vaccine for cancers. Gold nanoparticles enable efficient antigen delivery to dendritic cells and then activate the cells to facilitate cross-presentation, inducing antigen-specific cytotoxic T-lymphocyte responses for effective cancer therapy.

Keywords: cancer vaccines; extra domain B; gold nanoparticles; immunotherapy; tumor-associated antigens.

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