Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2014 Mar 18;33(6):540-1.
doi: 10.1002/embj.201387548.

Response to Zhang et al

Amit Anand  1 , Toshie Kai
Affiliations
Comment

Response to Zhang et al

Amit Anand et al. EMBO J. .
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Immunostaining for piRNA pathway components, Tej, Krimp, Aub and Ago3 in qinkumo heterozygous and transheterozygote, qinkumo/Df ovaries. More than 80% of qinkumo/Df egg chambers showed mislocalization of Tudor domain proteins, Tej (41/52) and Krimp (46/53), and more than 70% egg chambers showed mislocalization of Piwi-family protein Aub (36/52) and Ago3 (35/48).
See this image and copyright information in PMC

Comment on

References

    1. Anand A, Kai T. The tudor domain protein kumo is required to assemble the nuage and to generate germline piRNAs in Drosophila. EMBO J. 2012;31:870–882. - PMC - PubMed
    1. Handler D, Olivieri D, Novatchkova M, Gruber FS, Meixner K, Mechtler K, Stark A, Sachidanandam R, Brennecke J. A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors. EMBO J. 2011;30:3977–3993. - PMC - PubMed
    1. Malone CD, Brennecke J, Dus M, Stark A, McCombie WR, Sachidanandam R, Hannon GJ. Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary. Cell. 2009;137:522–535. - PMC - PubMed
    1. Taft RJ, Glazov EA, Lassmann T, Hayashizaki Y, Carninci P, Mattick JS. Small RNAs derived from snoRNAs. RNA. 2009;15:1233–1240. - PMC - PubMed
    1. Zhang Z, Koppetsch B, Wang J, Tipping C, Weng Z, Theurkauf WE, Zamore PD. Antisense piRNA amplification, but not piRNA production or nuage assembly, requires the Tudor-domain protein Qin. EMBO J. 2014;33:536–539. - PMC - PubMed

LinkOut - more resources