Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Nov 2;11(1):205-8.
eCollection 2014.

A study on the antidepressant effect of Danzhi Xiaoyao Powder

Zheng Lun  1
Affiliations

A study on the antidepressant effect of Danzhi Xiaoyao Powder

Zheng Lun. Afr J Tradit Complement Altern Med. .

Abstract

Background: Danzhi Xiaoyao Powder is used for regulating qi and blood, soothing liver-qi stagnation and adjusting the function of internal organs in the clinical. The objective of this paper was to study the antidepressant effect of Danzhi Xiaoyao Powder.

Methods: Experimental animals were grouped and given different doses of xiaoyao powder and Fluoxetine Hydrochloride tablets respectively. Mouse models of behavioural despair such as tail suspension test and forced swimming test were used to evaluate the antidepressant effect of Xiaoyao.

Results: Danzhi Xiaoyao Powder could shorten the immobility time of mice in the tail suspension and forced swimming despair models, and had a significant effect on them, while having no significant effect on locomotor activity in mice.

Conclusion: Danzhi Xiaoyao Powder has a good antidepressant effect. The material basis and physiological and biochemical mechanisms of its action should be determined by further study.

Keywords: Danzhi Xiaoyao Powder; anti-depression; forced swimming test; tail suspension test.

PubMed Disclaimer

References

    1. He Yong-mei, Du Shao-li. Advancement in research on antidepressant TCM. Hunan Guiding Journal of Traditional Chinese Medicine and Pharmacology. 2003;9(6):71–73.
    1. Hou Lin, Li Yan-hua, Wang Jing-jun. New advances in the study of antidepressants. Medical Recapitulate. 2007;13(19):1511–15116.
    1. Li Yi-kui. Experimental Methodology of TCM Pharmacology. Shanghai: Shanghai Scientific & Technical Publishers; 1991. pp. 329–331.
    1. Liu Yue, Gu Wei. Professor Huang Huang's experience in application of Banxia Houpu Decoction. Forum On Traditional Chinese Medicine. 1998;13(4):24–25.
    1. Nixon MK. Additive effects of Lithium and antidepressants in the forced swimming test: further evidence for involvement of the serotoninergic system. Psychopharmacology. 1994;115:59–64. - PubMed

LinkOut - more resources