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Review
. 2014 Mar 15;7(1):37-41.
Epub 2014 Mar 25.

Osteoarthritis pathogenesis - a complex process that involves the entire joint

G S Man  1 , G Mologhianu  2
Affiliations
Review

Osteoarthritis pathogenesis - a complex process that involves the entire joint

G S Man et al. J Med Life. .

Abstract

Osteoarthritis is the most common joint disorder and a major cause of disability with a major socio-economic impact. In these circumstances is very important to understand its pathogenesis. Although previous research focused primarily on changes in the articular cartilage, more recent studies have highlighted the importance of the subchondral bone, synovium, menisci, ligaments, periarticular muscles and nerves. Now osteoarthritis is viewed as a multifactorial disease affecting the whole joint.

Keywords: cartilage; menisci; osteoarthritis; subchondral bone; synovium.

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