Antimalarials in dermatology: mechanism of action, indications, and side effects

Abstract

Antimalarial drugs have been in common use in dermatology since the 1950s. Their mechanism of action is complex, and it is now known that they act through various pathways. We review the indications for antimalarials in dermatology, their adverse effects, and some less well-known effects, such as their antithrombotic and hypolipidemic action. The most recent recommendations concerning ophthalmological screening in patients on antimalarials are also reviewed.

Keywords: Antimalarials; Antipalúdicos; Chloroquine; Cloroquina; Hidroxicloroquina; Hydroxychloroquine; Lupus eritematoso; Lupus erythematosus.