The light touch of delta opioid receptors
- PMID: 24656246
- DOI: 10.1016/j.neuron.2014.03.004
The light touch of delta opioid receptors
Abstract
Expression of δ-opioid receptors in sensory neurons is controversial. In this issue of Neuron, Bardoni et al. (2014) present evidence that DOPrs are expressed on mechanosensory neurons involved in detecting nonnoxious touch but are very sparse in μ-opioid receptor-rich nociceptive neurons.
Copyright © 2014 Elsevier Inc. All rights reserved.
Comment on
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Delta opioid receptors presynaptically regulate cutaneous mechanosensory neuron input to the spinal cord dorsal horn.Neuron. 2014 Mar 19;81(6):1312-1327. doi: 10.1016/j.neuron.2014.01.044. Epub 2014 Feb 27. Neuron. 2014. PMID: 24583022 Free PMC article.
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