Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits
- PMID: 2465923
- DOI: 10.1016/0014-5793(89)80563-0
Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits
Abstract
The deduced amino acid sequences of cDNA clones encoding human GABAA receptor alpha 1 and beta 1 subunits are presented. The human subunits display very high levels of sequence identity with the corresponding bovine receptor subunits. The cloned human GABAA receptor subunits induce the formation of GABA-gated chloride channels when expressed in mammalian cells.
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