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. 1989 Feb 27;244(2):361-4.
doi: 10.1016/0014-5793(89)80563-0.

Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits

P R Schofield  1 , D B Pritchett, H Sontheimer, H Kettenmann, P H Seeburg
Affiliations
Free article

Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits

P R Schofield et al. FEBS Lett. .
Free article

Abstract

The deduced amino acid sequences of cDNA clones encoding human GABAA receptor alpha 1 and beta 1 subunits are presented. The human subunits display very high levels of sequence identity with the corresponding bovine receptor subunits. The cloned human GABAA receptor subunits induce the formation of GABA-gated chloride channels when expressed in mammalian cells.

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