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Case Reports
. 2014 Feb;41(1):73-82.
doi: 10.1159/000357106. Epub 2013 Dec 23.

Usutu virus

Affiliations
Case Reports

Usutu virus

Georg Pauli et al. Transfus Med Hemother. 2014 Feb.
No abstract available

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Figures

Fig. 1
Fig. 1
Genome structure of USUV: C = capsid protein/capsid protein; prM = precursor of the membrane proteins; E = surface glycoprotein (envelope protein); NS = non-structural protein; UTR = non-translated region; Cap = structure at 5′ end; NS1 = inhibitor of signal transduction for innate immunity; NS2-NS2A = required for virus assembly and inhibitor of activation of the IFN-β promoter; NS3 = multifunctional protein: serine protease (co-factor NS2B), 5′-RNA-triphosphatase (RTPase), nucleoside-triphosphatase (NTPase) and ATP-dependent RNA helicase; NS4-NS4A = modifies the endoplasmic reticulum, NS4B blocks IFN response; NS5 = RNA-dependent RNA polymerase, N-7- and 2′O-methyltransferase (MTase) for methylation of the 5′-RNA-cap structure.

References

    1. Williams MC, Simpson DI, Haddow AJ, Knight EM. The isolation of West Nile Virus from man and of Usutu virus from the bird-biting mosquito Mansonia aurites (Theobald) in the Entebbe area of Uganda. Ann Trop Med Parasitol. 1964;58:367–374. - PubMed
    1. CRORA Senegal www.pasteur.fr/recherche/banques/CRORA/souches/sras1.html (retrieved 14 Sept 2012).
    1. CRORA RCA.www.pasteur.fr/recherche/banques/CRORA/souches/sqas1.html (retrieved 14 Sept 2012).
    1. Woodall JP. The viruses isolated from arthropods at the East African Virus Research Institute in the 26 years ending December 1963. Proc E Afr Acad. 1964;II:141–146.
    1. CRORA Flavivirus USUTU.www.pasteur.fr/recherche/banques/CRORA/virus/v010050.html (retrieved 14 Sept 2012).

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