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Review
. 2014 Aug;71(16):3081-99.
doi: 10.1007/s00018-014-1604-5. Epub 2014 Mar 25.

Comparative myogenesis in teleosts and mammals

Giuliana Rossi  1 , Graziella Messina
Affiliations
Review

Comparative myogenesis in teleosts and mammals

Giuliana Rossi et al. Cell Mol Life Sci. 2014 Aug.

Abstract

Skeletal myogenesis has been and is currently under extensive study in both mammals and teleosts, with the latter providing a good model for skeletal myogenesis because of their flexible and conserved genome. Parallel investigations of muscle studies using both these models have strongly accelerated the advances in the field. However, when transferring the knowledge from one model to the other, it is important to take into account both their similarities and differences. The main difficulties in comparing mammals and teleosts arise from their different temporal development. Conserved aspects can be seen for muscle developmental origin and segmentation, and for the presence of multiple myogenic waves. Among the divergences, many fish have an indeterminate growth capacity throughout their entire life span, which is absent in mammals, thus implying different post-natal growth mechanisms. This review covers the current state of the art on myogenesis, with a focus on the most conserved and divergent aspects between mammals and teleosts.

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Figures

Fig. 1
Fig. 1
Model of the early phases of myogenesis in mouse at embryonic day E10.5, illustrating how morphogens secreted by the surrounding domains can influence myogenic commitment. DM dermomyotome, DE dorsal ectoderm, NT neural tube, NC notochord, LM lateral mesoderm, MRFs myogenic regulatory factors
Fig. 2
Fig. 2
Scheme of myogenic lineages, myogenic waves, and the molecules responsible for pre-natal muscle development in mouse. MRFs myogenic regulatory factors, d.p.c. days post-coitum. An indicative timing of murine development is shown
Fig. 3
Fig. 3
Scheme of embryonic muscle development in zebrafish, showing a schematic flow chart of early muscle development where the main patterning events have been defined. h.p.f. hours post-fertilization, ABC anterior border cells, Row1 row of cells 1
Fig. 4
Fig. 4
Schematic representation of the molecular pathways that regulate fiber type diversification in zebrafish. In italics, specific slow and fast genes; see text for details
Fig. 5
Fig. 5
Comparative scheme of regenerative myogenesis in mammals and teleosts. Red highlights the main differences
See this image and copyright information in PMC

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