Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 Fall;6(4):27-31.

Iron status and febrile seizure- a case control study in children less than 3 years

Mansour Sadeghzadeh  1 , Parisa Khoshnevis Asl  1 , Esrafil Mahboubi  2
Affiliations

Iron status and febrile seizure- a case control study in children less than 3 years

Mansour Sadeghzadeh et al. Iran J Child Neurol. 2012 Fall.

Abstract

Objective: Febrile seizure is one of the most common neurological conditions of childhood. Several theories, such as iron deficiency anemia have been proposed as the pathogenesis of this condition. The aim of this study was to find the association between iron deficiency anemia and febrile seizures in children aged 6 months to 3 years admitted in Valie Asr hospital in Zanjan.

Materials &methods: Hemoglobin (Hb), mean corpuscular volume (MCV), serum iron (SI), total iron binding capacity (TIBC) and SI/TIBC ratio were assessed in one hundred children with febrile seizures and compared to the values of one hundred healthy children presenting in a heath care center in the same period as the control group.

Results: A total of 6% of cases had iron deficiency anemia which was similar to the control group. In the case group SI/TIBC ratio below 12% was seen in 58% of children which was significantly higher than that of the control group (29%).

Conclusion: The results of this study suggest that although anemia was not common among febrile seizure patients, iron deficiency was more frequent in these patients.

Keywords: Anemia; Febrile; Iron deficiency; Seizures.

PubMed Disclaimer

References

    1. Bidabadi E, Mashouf M. Association between iron deficiency anemia and first febrile convulsion: A casecontrol study. Seizure. 2009 Jan;18(5):347–51. - PubMed
    1. Sadeghzadeh M, Khoshnevisasl P, Moussavinassab N, Koosha A, Norouzi M. The Relation Between Serum Zinc Level and Febrile Seizures in Children Admitted to Zanjan Valie-Asr Hospital. J Zanjan Uni Med Sci. 2011;19(74):17–24.
    1. Kumari PL, Nair MK, Nair SM, Kailas L, Geetha S. Iron deficiency as a risk factor for simple febrile seizures-a case control study. Indian Pediatr. 2012 Jan;49(1):17–9. - PubMed
    1. Pisacane A, Sansone R, Impagliazzo N, Coppola A, Rolando P, D’Apuzzo A, Tregrossi C. Iron deficiency anaemia and febrile convulsions: case-control study in children under 2 years. BMJ. 1996 Aug;313(7053) - PMC - PubMed
    1. Yadav D, Chandra J. Iron deficiency: beyond anemia. Indian J Pediatr. 2011 Jan;78(1):65–72. - PubMed

LinkOut - more resources