[Ménétrieŕs disease associated with cytomegalovirus infection]

Abstract

Menetrier's disease is a rare entity in children, characterized by a protein-losing gastroenteropathy with thickening of the gastric mucosa and generalized edema. The most common etiology is viral, and cytomegalovirus is the agent most frequently implicated. Unlike in the adult, it is a self-limited disorder with a good prognosis in children. Four patients (three boys and one girl) diagnosed with Ménétrier disease in the past five years were reviewed. The mean age at presentation was 28.7 months (range: 10-48 months). The most common clinical symptoms were fever, vomiting, and edema. Endoscopy showed thickened gastric folds and erosions in several stages. All patients had an associated gastric cytomegalovirus infection, and a favorable outcome, with resolution of the disorder,was observed within a few weeks.

Keywords: Citomegalovirus; Cytomegalovirus; Enfermedad de Ménétrier; Gastroenteropatía pierde proteínas; Gastropatía hipertrófica; Hypertrophic gastropathy; Ménétrier disease; Protein-losing gastroenteropathy.