Callosal projections between areas 17 in the adult tree shrew (Tupaia belangeri)

Abstract

In the primary visual cortex (area 17) of the tree shrew (Tupaia belangeri) neurons projecting to the contralateral area 17 via the corpus callosum were identified by horseradish peroxidase histochemistry (HRP, WGA-HRP). The distribution of homotopic and heterotopic connections was studied. We found that a narrow stripe of area 17 close to the dorsal area 17/18 border - which corresponds to the visual field along the vertical meridian - is connected via homotopic callosal projections. The adjacent dorsal part of area 17, which largely corresponds to the binocular visual field, is connected via homotopic as well as heterotopic projections. Heterotopic projections originate in the cortical stripe along the area 17/18 border and their contralateral targets are displaced medially. Callosal neurons are located mostly in supragranular but also occur in infragranular layers. The supragranular neurons in general are pyramidal cells. In addition to these findings, we confirmed earlier reports on ipsilateral projections of the primary visual area to the dLGN, the claustrum, area 18 and other visual areas.