Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2014 Jan;4(1):140-2.
doi: 10.4103/2141-9248.126626.

Systemic lupus erythematosus presenting as acute adrenal insufficiency: a rare clinical presentation

Ra Bhat  1 , I Khan  1 , T Mir  1 , I Khan  2 , M Wani  3
Affiliations
Case Reports

Systemic lupus erythematosus presenting as acute adrenal insufficiency: a rare clinical presentation

Ra Bhat et al. Ann Med Health Sci Res. 2014 Jan.

Abstract

Systemic lupus erythematosus is a complex autoimmune disease with multisystem involvement with varied presentation. Autoimmune adrenal disease, on the other hand, can be associated with other autoimmune diseases. Adrenal insufficiency as a presenting feature of Systemic lupus erythematosus is a rare occurrence. We hereby report a case of a 20 year-old female who presented to us in an acute hypoadrenal state and was found to have Systemic lupus erythematosus with renal involvement. Patient was successfully managed with steroids and improved clinically.

Keywords: Addison's disease; Autoimmune diseases; Systemic lupus erythematosus.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Clinical photomicrograph showing Dark brown rash over face (red and green arrows) and dark pigmentation over lips (black arrow)
Figure 2
Figure 2
Histopathological examination of the Biopsy specimen showing Features of focal lupus nephritis (International society of nephrology/Renal pathology society class III, national institute of health activity score of 9/24 and chronicity 3/12)
See this image and copyright information in PMC

References

    1. Rahman A, Isenberg DA. Systemic lupus erythematosus. N Engl J Med. 2008;358:929–39. - PubMed
    1. Stewart PM. The adrenal cortex. In: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR, editors. Williams Textbook of Endocrinology. 11th ed. Saunders: An Imprint of Elsevier; 2008. pp. 477–8.
    1. Hahn BH. Systemic lupus erythematosus. In: Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL, Loscalzo J, editors. Harrison's Principles of Internal Medicine. 18th ed. USA: Mc Graw-Hill Companies; 2012. pp. 2724–35.
    1. Arlt W. Disease of the adrenal cortex. In: Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL, Loscalzo J, editors. Harrison's Principles of Internal Medicine. 18th ed. USA: Mc Graw-Hill Companies; 2012. pp. 2940–61.
    1. White K, Arlt W. Adrenal crisis in treated Addison's disease: A predictable but under-managed event. Eur J Endocrinol. 2010;162:115–20. - PubMed

Publication types