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. 2014 Mar-Apr;99(2):112-9.
doi: 10.9738/INTSURG-D-13-00059.

Incidence and mortality of anastomotic dehiscence requiring reoperation after rectal carcinoma resection

Zhi-jie Cong  1 , Liang-hao Hu, Jun-jie Xing, Zheng-qian Bian, Chuan-gang Fu, En-da Yu, Zhao-shen Li, Ming Zhong
Affiliations

Incidence and mortality of anastomotic dehiscence requiring reoperation after rectal carcinoma resection

Zhi-jie Cong et al. Int Surg. 2014 Mar-Apr.

Abstract

Anastomotic dehiscence (AD) requiring reoperation is the most severe complication following anterior rectal resection. We performed a systematic review on studies that describe AD requiring reoperation and its subsequent mortality after anterior resection for rectal carcinoma. A systematic search was performed on published literature. Data on the definition and rate of AD, the number of ADs requiring reoperation, the mortality caused by AD, and the overall postoperative mortality were pooled and analyzed. A total of 39 studies with 24,232 patients were analyzed. The studies varied in incidence and definition of AD. Systematic review of the data showed that the overall rate of AD was 8.6%, and the rate of AD requiring reoperation was 5.4%. The postoperative mortality caused by AD was 0.4%, and the overall postoperative mortality was 1.3%. We found considerable risk and mortality for AD requiring reoperation, which largely contributed to the overall postoperative mortality.

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Figures

Fig. 1
Fig. 1
Rates of AD and AD requiring reoperation over the studies.
Fig. 2
Fig. 2
Mortality rate caused by AD requiring reoperation and overall postoperative mortality over the studies.
See this image and copyright information in PMC

References

    1. Ptok H, Marusch F, Meyer F, Schubert D, Gastinger I, Lippert H. Impact of anastomotic leakage on oncological outcome after rectal cancer resection. Br J Surg. 2007;94(12):1548–1554. - PubMed
    1. Bell SW, Walker KG, Rickard MJ, Sinclair G, Dent OF, Chapuis PH. Anastomotic leakage after curative anterior resection results in a higher prevalence of local recurrence. Br J Surg. 2003;90(10):1261–1266. - PubMed
    1. Merkel S, Wang WY, Schmidt O, Dworak O, Wittekind C, Hohenberger W. Locoregional recurrence in patients with anastomotic leakage after anterior resection for rectal carcinoma. Colorectal Dis. 2001;3(3):154–160. - PubMed
    1. Kim SH, Park IJ, Joh YG. Laparoscopic resection of rectal cancer: a comparison of surgical and oncologic outcomes between extraperitoneal and intraperitoneal disease locations. Dis Colon Rectum. 2008;51(6):844–851. - PubMed
    1. Bretagnol F, Alves A, Ricci A, Valleur P, Panis Y. Rectal cancer surgery without mechanical bowel preparation. Br J Surg. 2007;94(10):1266–1271. - PubMed

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