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Editorial
. 2014 May 14;35(19):1231-4.
doi: 10.1093/eurheartj/ehu117. Epub 2014 Mar 26.

Regenerative heart failure therapy headed for optimization

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Editorial

Regenerative heart failure therapy headed for optimization

Andre Terzic et al. Eur Heart J. .
No abstract available

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Figures

Figure 1
Figure 1
Evolution of stem cell paradigms. Early experience in the treatment of cardiovascular diseases employs stem cells in their native state. This approach has yielded variable outcomes. Increasingly, strategies that would optimize outcome are implemented in clinical trials. These include combination approaches that augment the efficacy of primary therapy; organ conditioning to prepare target tissue for subsequent cell delivery; cell selection to purify the desired cell population; and next-generation approaches including cardiac stem cells and lineage-specified progenitors.

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References

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