doi: 10.1038/338557a0.
Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor
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- PMID: 2467210
- DOI: 10.1038/338557a0
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Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor
Nature.
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Abstract
Cloning and sequencing of the complementary DNA for platelet-derived endothelial cell growth factor indicates that it is a novel factor distinct from previously characterized proteins. The factor, a protein with a relative molecular mass of about 45,000, stimulates endothelial cell growth and chemotaxis in vitro and angiogenesis in vivo.
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