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Review
. 2013 Oct;6(4):220-6.
doi: 10.4103/0974-1208.126282.

Should mild stimulation be the order of the day?

Nalini Mahajan  1
Affiliations
Review

Should mild stimulation be the order of the day?

Nalini Mahajan. J Hum Reprod Sci. 2013 Oct.

Abstract

Mild stimulation protocols aim to reduce the physical, financial and emotional burden associated with the conventional IVF protocol without compromising the pregnancy rate. Such protocols help to decrease the complications and the discomfort related to the prolonged administration of agonist and large doses of gonadotrophins, by limiting the number of oocytes recruited to no more than eight. The per cycle pregnancy rates are lower though the cumulative pregnancy rate in a year is equivalent. This CPR comes by going through earlier repeat cycles. Whether this reduces the physical, emotional or financial burden remains a matter of debate. There is need to standardize these protocol and do more trials to compare the two effectively. Till such time there is a clear benefit above the conventional protocol it will not be the protocol of choice with most physicians.

Keywords: Gonadotrophins; in vitro fertilization; infertility; mild stimulation protocol.

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Conflict of interest statement

Conflict of Interest: None declared.

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