RHOA mutations in peripheral T cell lymphoma
- PMID: 24675518
- DOI: 10.1038/ng.2937
RHOA mutations in peripheral T cell lymphoma
Abstract
Peripheral T cell lymphomas are rare but aggressive non-Hodgkin lymphomas derived from mature T lymphocytes or natural killer (NK) cells. New studies identify recurrent dominant-negative mutation of the RHOA GTPase gene in these lymphomas.
Comment on
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A recurrent inactivating mutation in RHOA GTPase in angioimmunoblastic T cell lymphoma.Nat Genet. 2014 Apr;46(4):371-5. doi: 10.1038/ng.2916. Epub 2014 Mar 2. Nat Genet. 2014. PMID: 24584070
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