Cyclin D1 transcriptional activation in MCL
- PMID: 24677400
- DOI: 10.1182/blood-2014-02-553057
Cyclin D1 transcriptional activation in MCL
Abstract
In this issue of Blood, Allinne et al propose the nucleolin-dependent activation of the translocated CCND1 allele in mantle cell lymphoma (MCL) because of its relocalization to a transcriptionally favorable area in the perinucleolar region.
Comment on
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Perinucleolar relocalization and nucleolin as crucial events in the transcriptional activation of key genes in mantle cell lymphoma.Blood. 2014 Mar 27;123(13):2044-53. doi: 10.1182/blood-2013-06-510511. Epub 2014 Jan 22. Blood. 2014. PMID: 24452204
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