Botulinum toxin: The Midas touch
- PMID: 24678189
- PMCID: PMC3961958
- DOI: 10.4103/0976-9668.127274
Botulinum toxin: The Midas touch
Abstract
Botulinum Toxin (BT) is a natural molecule produced during growth and autolysis of bacterium called Clostridium botulinum. Use of BT for cosmetic purposes has gained popularity over past two decades, and recently, other therapeutic uses of BT has been extensively studied. BT is considered as a minimally invasive agent that can be used in the treatment of various orofacial disorders and improving the quality of life in such patients. The objective of this article is to review the nature, mechanism of action of BT, and its application in various head and neck diseases.
Keywords: Botulinum toxin; head and neck disease; temperomandibular diseases.
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References
-
- Arnon SS, Schechter R, Inglesby TV, Henderson DA, Bartlett JG, Ascher MS, et al. Botulinum toxin as a biological weapon: Medical and public health management. JAMA. 2001;285:1059–70. - PubMed
-
- Scott AB. Botulinum toxin injection into extraocular muscles as an alternative to strabismus surgery. Opthalmology. 1980;87:1044–9. - PubMed
-
- Hoque A, McAndrew M. Use of botulinum toxin in dentistry. N Y State Dent J. 2009;75:52–5. - PubMed
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