Review
[Bone and Stem Cells. Mesenchymal stem cells and bone regeneration]
[Article in
Japanese]
Affiliations
- PMID: 24681503
Item in Clipboard
Review
[Bone and Stem Cells. Mesenchymal stem cells and bone regeneration]
[Article in
Japanese]
Clin Calcium.
2014 Apr.
Abstract
Mesenchymal stem cells (MSCs) have multi-differentiation potency, and enhance wound healing in various kinds of disease. Recently MSC not only differentiate into tissue-forming cells, but also secrete various kinds of cytokines and chemokines that are anti-apoptotic, immunomodulatory, angiogenic, and the cell-mobilizing to influence extracellular environment. In addition, we show that MSC has a novel intercellular communication mechanism. It hopes to suggest ways to make safer and reliable usage of MSC in bone regeneration.
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