High prevalence of Helicobacter pylori infection in Behcet's disease
- PMID: 24684898
- PMCID: PMC3994270
- DOI: 10.1186/1471-230X-14-58
High prevalence of Helicobacter pylori infection in Behcet's disease
Abstract
Background: Behcet's disease (BD) is a multisystem disease of unknown etiology. There are several clues which may indicate an ethiopathogenesis role for Helicobacter pylori infection in this disease.
Methods: In a case control study in an out patient department, 48 patients with BD were compared to age, sex matched controls regarding presence of H. pylori infection by serology and urea breath test (UBT).
Results: Ongoing H. pylori infection was more prevalent among patients with BD using result of UBT with odds ratio of 3.1 (95% CI: 1.34 - 7.26, PV < 0.001).
Conclusion: H. pylori infection may have a role in the pathogenesis of BD.
References
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- Pleyer U, Hazirolan D, Stubiger N. Comments on the pathogenesis of Behcet’s disease. A key to understanding new therapies? Ophthalmologe. 2012;109(6):563–567. doi: 10.1007/s00347-012-2586-z. Epub 2012/06/16. Anmerkungen zur Pathogenese des Morbus Behcet. Ein Schlussel zum Verstandnis neuer Therapien? - DOI - PubMed
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