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Randomized Controlled Trial
. 2014 Apr;133(4):e875-83.
doi: 10.1542/peds.2013-2246. Epub 2014 Mar 31.

Impact of the FITKids physical activity intervention on adiposity in prepubertal children

Naiman A Khan  1 , Lauren B Raine, Eric S Drollette, Mark R Scudder, Matthew B Pontifex, Darla M Castelli, Sharon M Donovan, Ellen M Evans, Charles H Hillman
Affiliations
Randomized Controlled Trial

Impact of the FITKids physical activity intervention on adiposity in prepubertal children

Naiman A Khan et al. Pediatrics. 2014 Apr.

Abstract

Objective: To investigate the effect of a 9-month physical activity intervention on cardiorespiratory fitness and adiposity among prepubertal children.

Methods: Prepubertal children (8- to 9-year-olds, N = 220, 103 girls) were randomly assigned to a 9-month physical activity intervention or a control group. The intervention provided 70 minutes (5 days/week) of moderate to vigorous physical activity. Maximum oxygen consumption (Vo2max percentile) and dual-energy radiograph absorptiometry measured cardiorespiratory fitness and adiposity, respectively. Intention-to-treat analysis was performed to assess baseline and follow-up cardiorespiratory fitness, percentage fat mass (%FM), percentage central fat mass (%CFM), and estimated visceral adipose tissue (VAT) area.

Results: The intervention group increased in cardiorespiratory fitness (5.4th percentile; 95% confidence interval [CI], 1.8 to 8.9) and decreased in %FM (-0.7%; 95% CI, -1.1 to -0.4) and %CFM (-1.3%; 95% CI, -1.9 to -0.7). Reductions in %FM were evident for both nonoverweight (-0.62%; 95% CI, -1.07 to -0.17) and overweight or obese (-0.86%; 95% CI,-1.46 to -0.25) intervention participants. Conversely, the control group displayed no change in cardiorespiratory fitness while exhibiting increases in %FM (0.4%; 95% CI, 0.1 to 0.7), %CFM (0.6; 95% CI, 0.1 to 1.1), and VAT area (3.0 cm(2); 95% CI, 1.6 to 4.4). Nonoverweight control participants increased in %FM (0.52%; 95% CI, 0.13 to 0.91), and their overweight and obese counterparts increased in VAT (4.76 cm(2); 95% CI, 1.90 to 7.63).

Conclusions: The physical activity intervention improved cardiorespiratory fitness, reduced %FM, and prevented accumulation of %CFM among prepubertal children with varying adiposity levels. These findings provide support for daily physical activity recommendations to prevent excess fat mass accumulation in childhood.

Trial registration: ClinicalTrials.gov NCT01334359.

Keywords: abdominal adiposity; obesity; physical activity; physical fitness.

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Figures

FIGURE 1
FIGURE 1
Participant flow through the study.
FIGURE 2
FIGURE 2
Baseline to follow-up changes. A, Cardiorespiratory fitness. B, BMI z score. C, Percentage whole body fat. D, Percentage central fat mass. All values are mean (SEM). *Change from baseline to follow-up is significantly different between intervention and control groups (P < .05).
See this image and copyright information in PMC

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