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. 1989 Feb;14(2):141-50.
doi: 10.1111/j.1365-2559.1989.tb02124.x.

Immunoreactive cytokeratins in plasmacytomas

A C Wotherspoon  1 , A J Norton, P G Isaacson
Affiliations

Immunoreactive cytokeratins in plasmacytomas

A C Wotherspoon et al. Histopathology. 1989 Feb.

Abstract

Fourteen plasma cell tumours, including examples of solitary plasmacytoma and multiple myeloma, were studied with a panel of antibodies reactive in formalin-fixed, paraffin wax-embedded tissue. Each case showed immunoglobulin light chain restriction. Five tumours were reactive with antibodies to cytokeratin. Of these five cases, four were negative with antibodies to leucocyte common antigen and only one was weakly positive. Anti-cytokeratin reactivity by plasma cell tumours is more common than was originally anticipated and represents an important diagnostic pitfall.

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Comment in

  • Cytokeratins in plasmacytomas.
    Haboubi NY, Clark P. Haboubi NY, et al. Histopathology. 1990 Nov;17(5):482. doi: 10.1111/j.1365-2559.1990.tb00779.x. Histopathology. 1990. PMID: 1706301 No abstract available.
  • Cytokeratins in plasmacytomas.
    Battifora H. Battifora H. Histopathology. 1989 Sep;15(3):321-2. doi: 10.1111/j.1365-2559.1989.tb03097.x. Histopathology. 1989. PMID: 2478440 No abstract available.

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