Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2014 Jul;233(3):215-6.
doi: 10.1002/path.4355.

Sustained autoimmune mechanisms in dermatomyositis

Steven A Greenberg  1
Affiliations
Comment

Sustained autoimmune mechanisms in dermatomyositis

Steven A Greenberg. J Pathol. 2014 Jul.

Abstract

Dermatomyositis is an autoimmune disease predominantly affecting skin and muscle. Its poorly understood pathogenesis is increasingly being linked to the overproduction of type 1 interferon-inducible gene transcripts and proteins. Mechanisms have been identified by which chronic sustained accumulation of these proteins might occur and thereby injure tissue in dermatomyositis.

Keywords: dermatomyositis; innate immune system; type 1 interferon.

PubMed Disclaimer

Comment on

LinkOut - more resources