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Meta-Analysis
. 2014 Feb 15;7(3):932-7.
eCollection 2014.

Risk factors for central lymph node metastasis of patients with papillary thyroid microcarcinoma: a meta-analysis

Zeming Liu  1 , Longqiang Wang  1 , Pengfei Yi  1 , Cong-Yi Wang  2 , Tao Huang  1
Affiliations
Meta-Analysis

Risk factors for central lymph node metastasis of patients with papillary thyroid microcarcinoma: a meta-analysis

Zeming Liu et al. Int J Clin Exp Pathol. .

Abstract

Objective: To evaluate the risk factors of central lymph node metastasis of papillary thyroid microcarcinoma.

Method: Published articles about papillary thyroid microcarcinoma were searched in PubMed, MEDLINE and EMBASE until October 2013 to examine the risky factors of central lymph node metastasis. Software RevMan 5.0 was used for meta-analysis.

Results: Within the patients suffering papillary thyroid microcarcinoma underwent thyroidectomy plus prophylactic central lymph node dissection, tumor size, multifocality and capsular invasion have statistically relevant association with central lymph node metastasis, but no relation was observed associated with sex and age.

Conclusion: The papillary thyroid microcarcinoma should be considered central lymph node metastasis when tumor size ≥0.5 cm, multifocality and have capsular invasion.

Keywords: Risk factors; central lymph node metastasis; papillary thyroid carcinoma.

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Figures

Figure 1
Figure 1
Flow chart for articles identified and included in the meta-analysis.
Figure 2
Figure 2
Tumor size and central lymph node metastasis.
Figure 3
Figure 3
Foci number and central lymph node metastasis.
Figure 4
Figure 4
Age and central lymph node metastasis.
Figure 5
Figure 5
Sex and central lymph node metastasis.
Figure 6
Figure 6
Capsulate invasion and central lymph node metastasis.
See this image and copyright information in PMC

References

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    1. Kutler DI, Crummey AD, Kuhel WI. Routine central compartment lymph node dissection for patients with papillary thyroid carcinoma. Head Neck. 2012;34:260–263. - PubMed

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