Motor systems: reaching out and grasping the molecular tools
- PMID: 24698373
- DOI: 10.1016/j.cub.2014.02.048
Motor systems: reaching out and grasping the molecular tools
Abstract
Two recent studies provide important insights into the organization of premotor circuitries, showing that control of highly-specific skilled forelimb movements, such as reaching and grasping, requires activation of specific subpopulations of neurons in the brainstem and spinal cord.
Copyright © 2014 Elsevier Ltd. All rights reserved.
Comment on
-
Skilled reaching relies on a V2a propriospinal internal copy circuit.Nature. 2014 Apr 17;508(7496):357-63. doi: 10.1038/nature13021. Epub 2014 Feb 2. Nature. 2014. PMID: 24487617 Free PMC article.
-
Brainstem nucleus MdV mediates skilled forelimb motor tasks.Nature. 2014 Apr 17;508(7496):351-6. doi: 10.1038/nature13023. Epub 2014 Feb 2. Nature. 2014. PMID: 24487621
Similar articles
-
Brainstem nucleus MdV mediates skilled forelimb motor tasks.Nature. 2014 Apr 17;508(7496):351-6. doi: 10.1038/nature13023. Epub 2014 Feb 2. Nature. 2014. PMID: 24487621
-
Skilled reaching relies on a V2a propriospinal internal copy circuit.Nature. 2014 Apr 17;508(7496):357-63. doi: 10.1038/nature13021. Epub 2014 Feb 2. Nature. 2014. PMID: 24487617 Free PMC article.
-
On the origin of skilled forelimb movements.Trends Neurosci. 2000 Aug;23(8):372-6. doi: 10.1016/s0166-2236(00)01618-0. Trends Neurosci. 2000. PMID: 10906801 Review.
-
Neuroscience. Shortcuts and checkpoints on the road to skilled movement.Science. 2014 Oct 31;346(6209):554-5. doi: 10.1126/science.1260778. Science. 2014. PMID: 25359954 No abstract available.
-
Circuits for skilled reaching and grasping.Annu Rev Neurosci. 2012;35:559-78. doi: 10.1146/annurev-neuro-062111-150527. Epub 2012 Apr 9. Annu Rev Neurosci. 2012. PMID: 22524789 Review.
Cited by
-
Computations in Sensorimotor Learning.Cold Spring Harb Symp Quant Biol. 2014;79:93-8. doi: 10.1101/sqb.2014.79.024919. Epub 2015 Apr 7. Cold Spring Harb Symp Quant Biol. 2014. PMID: 25851507 Free PMC article. Review.
-
Facilitation of mossy fibre-driven spiking in the cerebellar nuclei by the synchrony of inhibition.J Physiol. 2017 Aug 1;595(15):5245-5264. doi: 10.1113/JP274321. Epub 2017 Jun 11. J Physiol. 2017. PMID: 28513836 Free PMC article.
-
Motor cortical inactivation impairs corrective submovements in mice performing a hold-still center-out reach task.J Neurophysiol. 2024 Sep 1;132(3):829-848. doi: 10.1152/jn.00241.2023. Epub 2024 Jul 31. J Neurophysiol. 2024. PMID: 39081209
-
Cerebellar control of gait and interlimb coordination.Brain Struct Funct. 2015 Nov;220(6):3513-36. doi: 10.1007/s00429-014-0870-1. Epub 2014 Aug 20. Brain Struct Funct. 2015. PMID: 25139623 Free PMC article.
-
Plasticity of subcortical pathways promote recovery of skilled hand function in rats after corticospinal and rubrospinal tract injuries.Exp Neurol. 2015 Apr;266:112-9. doi: 10.1016/j.expneurol.2015.01.009. Epub 2015 Feb 7. Exp Neurol. 2015. PMID: 25666586 Free PMC article.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources