Cell growth: when less means more

Affiliations

¹ 3601 4(th) St Rm 5C119, Department of Cell Biology and Biochemistry, Texas Tech University, Health Sciences Center, Lubbock, TX 79430, USA.
² 3601 4(th) St Rm 5C119, Department of Cell Biology and Biochemistry, Texas Tech University, Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: brandt.schneider@ttuhsc.edu.

Free article

Comment

Jill Wright et al. Curr Biol. 2014.

Free article

. 2014 Mar 31;24(7):R283-5.

doi: 10.1016/j.cub.2014.02.044.

¹ 3601 4(th) St Rm 5C119, Department of Cell Biology and Biochemistry, Texas Tech University, Health Sciences Center, Lubbock, TX 79430, USA.
² 3601 4(th) St Rm 5C119, Department of Cell Biology and Biochemistry, Texas Tech University, Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: brandt.schneider@ttuhsc.edu.

Abstract

When is less more? A new study reveals that decreased mitochondrial gene expression and reduced lipid biosynthesis may actually increase cell growth.

Identification of transcriptional and metabolic programs related to mammalian cell size.
Miettinen TP, Pessa HK, Caldez MJ, Fuhrer T, Diril MK, Sauer U, Kaldis P, Björklund M. Miettinen TP, et al. Curr Biol. 2014 Mar 17;24(6):598-608. doi: 10.1016/j.cub.2014.01.071. Epub 2014 Mar 6. Curr Biol. 2014. PMID: 24613310 Free PMC article.