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. 2014 Jul;21(7):1106-11.
doi: 10.1016/j.jocn.2014.01.003. Epub 2014 Jan 31.

Malignant peripheral nerve sheath tumors of the spine: a SEER database analysis

James A Stadler 3rd  1 , Usama Qadri  1 , Jessica A Tang  1 , Justin K Scheer  1 , Stephanie C Melkonian  2 , Zachary A Smith  1 , Sandi K Lam  3
Affiliations

Malignant peripheral nerve sheath tumors of the spine: a SEER database analysis

James A Stadler 3rd et al. J Clin Neurosci. 2014 Jul.

Abstract

Peripheral nerve sheath tumors are uncommon neoplasms that can affect any area of the body. Spinal lesions, especially those that are malignant, pose difficult management challenges, and data regarding these lesions are limited by the disease rarity. This study provides a population-based analysis using the Surveillance, Epidemiology, and End Results (SEER) database, focusing on patient characteristics and treatments. Surgery is associated with improved survival, whereas radiation therapy is associated with decreased survival in this cohort with malignant peripheral nerve sheath tumor in the spine.

Keywords: MPNST; Peripheral nerve sheath tumor; Radiation therapy; SEER database; Spine surgery.

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