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. 2014 Mar;59(2):209.
doi: 10.4103/0019-5154.127711.

Syphilitic hepatitis: an uncommon manifestation of a common disease

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Syphilitic hepatitis: an uncommon manifestation of a common disease

Sukriti Baveja et al. Indian J Dermatol. 2014 Mar.

Abstract

Hepatitis being first manifestation of secondary syphilis is rare. Here in we report a case of 39 years old male who was being treated for hepatitis and presented to us subsequently with itchy maculopapular rash. Venereal disease research laboratory (VDRL) titre was 1:16. Treponema pallidum hemagglutination assay (TPHA) was positive. He was treated with intramuscular Benzathine Penicillin. His hepatitis improved rapidly.

Keywords: Secondary syphilis; syphilitic hepatitis; treatment of syphilitic hepatitis.

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Conflict of interest statement

Conflict of Interest: Nil.

Figures

Figure 1
Figure 1
Erythematous scaly macules and papules over both palms
Figure 2
Figure 2
Congestion of soft palate
Figure 3
Figure 3
Erythematous macules and papules over neck
Figure 4
Figure 4
Erythematous macules and papules over back
Figure 5
Figure 5
Kupffer cell hyperplasia, lymphocytic and neutrophillic infiltration of portal tracts with mild neutrophillic infiltrate in hepatic lobules

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References

    1. Tramont EC. Treponema pallidum (syphilis) In: Mandell GL, Bennett JE, Dolin R, editors. Mandell, Douglas and Bennett's Principles and Practice of Infectious Diseases. 5th ed. Philadelphia: Livingstone; 2000. pp. 2474–90.
    1. Tiliakos N, Shamma’a JM, Nasrallah SM. Syphilitic hepatitis. Am J Gastroenterol. 1980;73:60–1. - PubMed
    1. Agrwal NM, Sassaris M, Brooks B, Akdamar K, Hunter F. The liver in secondary syphilis. South Med J. 1982;75:1136–8. - PubMed
    1. Schlossberg D. Syphilitic hepatitis: A case report and review of the literature. Am J Gastroenterol. 1987;82:552–3. - PubMed
    1. Mullick CJ, Liappis AP, Benator DA, Roberts AD, Parenti DM, Simon GL. Syphilitic hepatitis in HIV-Infected patients: A report of 7 cases and review of the literature. Clin Infect Dis. 2004;39:e100–5. - PubMed

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