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Case Reports
. 2014 Mar;24(2):110-3.
doi: 10.4103/0971-4065.127900.

Atypical presentation of post infectious glomerulonephritis as malignant hypertension and thrombotic microangiopathy

M Vankalakunti  1 , P Malleshappa  2 , H Hussain  3 , A Marilingegouda  4
Affiliations
Case Reports

Atypical presentation of post infectious glomerulonephritis as malignant hypertension and thrombotic microangiopathy

M Vankalakunti et al. Indian J Nephrol. 2014 Mar.

Abstract

Infection-related glomerulonephritis presents commonly as acute nephritic illness, hypertension, hypocomplementinemia following an episode of pharyngitis or pyoderma. Atypical features like thrombotic microangiopathy (TMA), produced by neuraminidase antigen targeting endothelium have been described rarely. We report a case of TMA secondary to malignant hypertension, coexisting with post infectious glomerulonephritis.

Keywords: Kidney biopsy; malignant hypertension; post infectious glomerulonephritis; thrombotic microangiopathy.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Solid and proliferative tufts comprising neutrophilic infiltration, obliterating capillary lumen. Basement membranes are single contoured (periodic acid Schiff, ×40)
Figure 2
Figure 2
Globally proliferative tuft with circumferential active crescent. Basement membranes are single contoured (Periodic Schiff-Methenamine Silver, ×40)
Figure 3
Figure 3
Glomerulus revealing blood filled and engorged capillaries with mesangiolysis (H and E, ×40)
Figure 4
Figure 4
Diffuse and global, coarse granular deposits along the capillary walls and mesangium with C3 (3+)
See this image and copyright information in PMC

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