Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2013 Jul;5(2):139-41.
doi: 10.4103/0974-2727.119875.

Periampullary adenocarcinoid: diagnostic dilemma

Rashmi Krishnappa  1 , Sudha Horakerappa Metikurke  1 , Sridhar Honnappa  1 , Rudresh Hosakote  2 , Nagesh Kumar Talkad Chandrashekar  3
Affiliations
Case Reports

Periampullary adenocarcinoid: diagnostic dilemma

Rashmi Krishnappa et al. J Lab Physicians. 2013 Jul.

Abstract

The growth in periampullary region needs proper evaluation as they can arise from duodenum, pancreas and extra hepatic biliary tree. We have reported a case of adenocarcinoid of duodenum presenting as periampullary growth with obstructive jaundice. Histologically, tumor displayed biphasic pattern, i.e. tubuloglandular architecture with admixed sheets of neuroendocrine cells without pancreas and extra hepatic biliary tree involvement. The adenocarcinoids are of great diagnostic challenges for the pathologist interpreting endoscopic biopsy for the frequent misinterpretation as negative due to their submucosal location or as adenocarcinomas due to tubulo-glandular architecture.

Keywords: Adenocarcinoids; carcinoids; periampullary region.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Gross photograph of periampullary mass measuring 2 × 1 cms in submucosal region
Figure 2
Figure 2
Microphotograph of tumor displaying both nests and tubular arrangement of cells (×400)
Figure 3
Figure 3
Microphotograph of peripancreatic lymphnode showing tumor metastasis (×400)
See this image and copyright information in PMC

References

    1. Costantini M, Montalti R, Rossi G, Luisa L, Masetti M, Di Benedetto F, et al. Adenocarcinoids tumor of extra hepatic biliary tree. Int J Surg Pathol. 2008;16:455–57. - PubMed
    1. Levy AD, Taylor LD, Abboth RM, Sobin LH. Duodenal carcinoids: Imaging features with clinical - pathological comparison. Radiology. 2005;237:967–72. - PubMed
    1. Levendoglu H, Cox CA, Nadimpalli V. Composite (adenocarcinoid) tumor of gastrointestinal tract. Dig Dis Sci. 1990;35:519–25. - PubMed
    1. Hatzitheoklitos E, Buchler MW, Friess H, Poch B, Ebert M, Mohr W, et al. Carcinoids of ampulla of vater. Clinical characteristics and morphological features. Cancer. 1994;73:1580–8. - PubMed
    1. Ferrando Marco J, Pallas Regueira A, Moro Valdezate D, Fernandez Martinez C. Collision tumor of the ampulla of Vater: Carcinoid and adenocarcinoma. Rev Esp Enferm Dig. 2007;99:235–8. - PubMed

Publication types