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Case Reports
. 2014 Feb;8(2):147-8.
doi: 10.7860/JCDR/2014/6811.4036. Epub 2014 Feb 3.

Small cell neuroendocrine carcinoma of the cervix: a rare entity

Pavithra V  1 , C N Sai Shalini  1 , Shanmuga Priya  1 , Usha Rani  2 , S Rajendiran  3 , Leena Dennis Joseph  3
Affiliations
Case Reports

Small cell neuroendocrine carcinoma of the cervix: a rare entity

Pavithra V et al. J Clin Diagn Res. 2014 Feb.

Abstract

Small cell carcinoma of the cervix is a rare and a very aggressive tumour. Once being considered to be a rare type of squamous cell carcinoma, evidence has proven that most of the tumours express one or more markers of neuroendocrine differentiation. The behaviour of this rare malignancy is different from that of squamous cell carcinomas, with a high propensity for nodal and distant metastases. Hence, there is a need to highlight this histopathological entity.

Keywords: Cervix; Neuroendocrine; Small cell.

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Figures

[Table/Fig-1]:
[Table/Fig-1]:
Cervix – Small round blue cells (H&E 200x)
[Table/Fig-2]:
[Table/Fig-2]:
Cervix –Small round blue cells (H&E 400x)
[Table/Fig-3]:
[Table/Fig-3]:
Cervix-Cytokeratin positivity (IHC 200x)
[Table/Fig-4]:
[Table/Fig-4]:
Cervix-Synaptophysin positivity (IHC 200x)
[Table/Fig-5]:
[Table/Fig-5]:
Cervix – CD 45 negativity (IHC 200x)
See this image and copyright information in PMC

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