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Case Reports
. 2014 Feb;8(2):177-8.
doi: 10.7860/JCDR/2014/6988.4051. Epub 2014 Feb 3.

Metastatic Primary Signet Ring Cell Carcinoma of Rectum: A Case Report of 10-Year-old Male Child

Kumkum Singh  1 , Amit Singh  2 , Shyam Bhutra  3 , Geeta Pachori  4 , Mahesh Kumar Jangir  5
Affiliations
Case Reports

Metastatic Primary Signet Ring Cell Carcinoma of Rectum: A Case Report of 10-Year-old Male Child

Kumkum Singh et al. J Clin Diagn Res. 2014 Feb.

Abstract

Signet ring cell carcinomas of the colon and rectum are well documented in the adult population, but the incidence is very low in the paediatric population. Signet ring cell carcinoma has more malignant potential, mostly present as advanced stage and carries very poor prognosis. We are describing a 10-year-old male patient who presented with acute intestinal obstruction; radiology revealed large bowel obstruction and was diagnosed metastatic primary signet ring cell carcinoma of rectum on biopsy. We have discussed the diagnostic work-up and the management of this rare entity. Due to the high mortality that can be caused by a delay in making the correct diagnosis, signet ring cell carcinoma of colorectum represents a special diagnostic and surgical challenge.

Keywords: Colorectal Neoplasm; Intestinal obstruction; Mucinous Tumor.

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Figures

[Table/Fig-1]:
[Table/Fig-1]:
Photomicrograph showing tumour cell having intracytoplasmic mucin pushing the nucleus to the periphery and giving a signet ring appearance (H&Ex100)
See this image and copyright information in PMC

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