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Comment
. 2014 Apr 3;14(4):417-8.
doi: 10.1016/j.stem.2014.03.007.

How Tets and cytoskeleton dynamics MET in reprogramming

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How Tets and cytoskeleton dynamics MET in reprogramming

Laurent David et al. Cell Stem Cell. .
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Abstract

Two studies by Sakurai et al. (2014) and Hu et al. (2014) in this issue of Cell Stem Cell add a new level of understanding to the mesenchymal-to-epithelial transition taking place during reprogramming, showing how this morphological transformation is promoted by Tet enzymes and blocked by kinase-dependent cytoskeletal organization.

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