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Comment
. 2014 Apr 3;14(4):419-20.
doi: 10.1016/j.stem.2014.03.006.

No monkeying around: clonal tracking of stem cells and progenitors in the macaque

Brad Dykstra  1 , Leonid V Bystrykh  2
Affiliations
Comment

No monkeying around: clonal tracking of stem cells and progenitors in the macaque

Brad Dykstra et al. Cell Stem Cell. .

Abstract

Clonal tracking of hematopoietic stem and progenitor cells (HSPCs) has proven valuable for studying their behavior in murine recipients. Now in Cell Stem Cell, Kim et al. (2014) and Wu et al. (2014) extend these analyses to nonhuman primates, providing insights into dynamics of HSPC expansion and lineage commitment following autologous transplantation.

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References

    1. Abramson S, Miller RG, Phillips RA. The identification in adult bone marrow of pluripotent and restricted stem cells of the myeloid and lymphoid systems. The Journal of experimental medicine. 1977;145:1567–1579. - PMC - PubMed
    1. Bystrykh LV, Verovskaya E, Zwart E, Broekhuis M, de Haan G. Counting stem cells: methodological constraints. Nature methods. 2012;9:567–574. - PubMed
    1. Copley MR, Beer PA, Eaves CJ. Hematopoietic stem cell heterogeneity takes center stage. Cell stem cell. 2012;10:690–697. - PubMed
    1. Doulatov S, Notta F, Eppert K, Nguyen LT, Ohashi PS, Dick JE. Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development. Nature immunology. 2010;11:585–593. - PubMed
    1. Gorgens A, Radtke S, Mollmann M, Cross M, Durig J, Horn PA, Giebel B. Revision of the human hematopoietic tree: granulocyte subtypes derive from distinct hematopoietic lineages. Cell reports. 2013;3:1539–1552. - PubMed