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Comment
. 2014 Apr 3;14(4):425-6.
doi: 10.1016/j.stem.2014.03.012.

Personalized platelet transfusions: one step closer to the clinic

Ji-Yoon Noh  1 , Mitchell J Weiss  2 , Mortimer Poncz  3
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Personalized platelet transfusions: one step closer to the clinic

Ji-Yoon Noh et al. Cell Stem Cell. .
Free article

Abstract

In this issue of Cell Stem Cell, Nakamura et al. (2014) use human pluripotent stem cells to generate immortalized megakaryocyte progenitor cell lines that can be cryopreserved, expanded in vitro, and induced to undergo terminal maturation and platelet release. This strategy advances efforts to produce clinically relevant numbers of tissue-culture-derived platelets for transfusion therapies.

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