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Review
. 2014 Mar:90 Suppl 1:S13-5.
doi: 10.1016/S0378-3782(14)70005-2.

Pharmacologic prevention of perinatal HIV infection

Natella Y Rakhmanina  1 , Johannes N van den Anker  2
Affiliations
Review

Pharmacologic prevention of perinatal HIV infection

Natella Y Rakhmanina et al. Early Hum Dev. 2014 Mar.

Abstract

The goal of antiretroviral therapy for the prevention of mother-to-child transmission (PMTCT) of HIV is to achieve maximal suppression of maternal viral load with minimal maternal, fetal and infant toxicity during pregnancy, delivery and postpartum. In addition to the efficacy and toxicity of antiretroviral therapy, the consideration of HIV resistance in mothers and infected newborns further complicates therapeutic choices for PMTCT. This manuscript summarizes current approaches to PMTC in diverse international settings.

Keywords: HIV; Perinatal; Prophylaxis; amntiretroviral.

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