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Review
. 2014 Mar:90 Suppl 1:S29-31.
doi: 10.1016/S0378-3782(14)70010-6.

Diagnosis and counseling of fetal and neonatal HCMV infection

Maurizio Zavattoni  1 , Milena Furione  2 , Alessia Arossa  3 , Angela Iasci  3 , Arsenio Spinillo  3 , Giuseppina Lombardi  4 , Mauro Stronati  4 , Andrea Righini  5 , Fausto Baldanti  2
Affiliations
Review

Diagnosis and counseling of fetal and neonatal HCMV infection

Maurizio Zavattoni et al. Early Hum Dev. 2014 Mar.

Abstract

Fetal HCMV infection is investigated by amniocentesis when a maternal primary infection is diagnosed or ultrasound (US/MRI) abnormalities are observed. In fetal blood, prognostic markers of symptomatic congenital infection may be evaluated for parental counseling. At birth, viral load measurement in body fluids may correlate with long-term sequelae, but the prognostic accuracy of symptomatic infection increases when maternal, fetal, and neonatal parameters are combined.

Keywords: Congenital infection; HCMV; Prognostic markers.

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