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. 2014 Mar;10(1):69-72.

Pigmented Basal cell carcinoma of nipple and areola in a male breast - a case report with review of literature

R Kalyani  1 , B R Vani  1 , Murthy V Srinivas  1 , P Veda  1
Affiliations

Pigmented Basal cell carcinoma of nipple and areola in a male breast - a case report with review of literature

R Kalyani et al. Int J Biomed Sci. 2014 Mar.

Abstract

Basal cell carcinoma is a common skin cancer worldwide. However basal cell carcinoma of nipple and areola complex is rare, commonly seen in males in elderly age group. The tumor has aggressive behavior with increased tendency for metastasis. We present a case in a 78 year male in the left breast.

Keywords: Basal cell carcinoma-nipple and areola complex; male breast; skin cancer.

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Figures

Figure 1
Figure 1
Microphotograph showing epidermis and dermis, lower end shows tumour cells in complex branching cords (single arrow) with upper end showing melanophages (double arrow) and focal tumour cells showing pallisading pattern (arrow head). H&E × 50.
Figure 2
Figure 2
Microphotograph showing tumour cells in cords with peripheral pallisading pattern (single arrow) and melanin pigment in the tumour cells (double arrow) and in stroma (arrow head). H&E × 100.
Figure 3
Figure 3
Microphotograph of tissue section with HMB 45 marker which shows negative in tumour cells (arrow) and positive with melanin pigment (arrow head). HMB45 × 100.
Figure 4
Figure 4
Microphotograph of tissue section with S100 marker which shows negative in tumour cells (arrow) and positive with melanin pigment (arrow head). S100 × 100.
See this image and copyright information in PMC

References

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